Comparative Metabolite Fingerprinting of Four Different Cinnamon Species Analyzed via UPLC–MS and GC–MS and Chemometric Tools
- authored by
- Mohamed A. Farag, Eman M. Kabbash, Ahmed Mediani, Stefanie Döll, Tuba Esatbeyoglu, Sherif M. Afifi
- Abstract
The present study aimed to assess metabolites heterogeneity among four major Cin-namomum species, including true cinnamon (Cinnamomum verum) and less explored species (C. cas-sia, C. iners, and C. tamala). UPLC-MS led to the annotation of 74 secondary metabolites belonging to different classes, including phenolic acids, tannins, flavonoids, and lignans. A new proanthocy-anidin was identified for the first time in C. tamala, along with several glycosylated flavonoid and dicarboxylic fatty acids reported for the first time in cinnamon. Multivariate data analyses revealed, for cinnamates, an abundance in C. verum versus procyandins, dihydro-coumaroylglycosides, and coumarin in C. cassia. A total of 51 primary metabolites were detected using GC-MS analysis en-compassing different classes, viz. sugars, fatty acids, and sugar alcohols, with true cinnamon from Malaysia suggested as a good sugar source for diabetic patients. Glycerol in C. tamala, erythritol in C. iners, and glucose and fructose in C. verum from Malaysia were major metabolites contributing to the discrimination among species.
- Organisation(s)
-
Institute of Food Science and Human Nutrition
Molecular Food Chemistry and Food Development
- External Organisation(s)
-
Cairo University
Universiti Kebangsaan Malaysia
Friedrich Schiller University Jena
University of Sadat City
- Type
- Article
- Journal
- Molecules
- Volume
- 27
- ISSN
- 1420-3049
- Publication date
- 04.05.2022
- Publication status
- Published
- Peer reviewed
- Yes
- ASJC Scopus subject areas
- Drug Discovery, Analytical Chemistry, Chemistry (miscellaneous), Molecular Medicine, Physical and Theoretical Chemistry, Pharmaceutical Science, Organic Chemistry
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Electronic version(s)
-
https://doi.org/10.3390/molecules27092935 (Access:
Open)
