Atlantic salmon (Salmo salar L.) as a marine functional source of gamma-tocopherol

verfasst von
D. Menoyo, C. Sanz-Bayón, A.H. Nessa, T. Esatbeyoglu, M. Faizan, K. Pallauf, N. De Diego, A.E. Wagner, I. Ipharraguerre, I. Stubhaug, G. Rimbach
Abstract

Gamma tocopherol (gT) exhibits beneficial cardiovascular effects partly due to its anti-inflammatory activity. Important sources of gT are vegetable oils. However, little is known to what extent gT can be transferred into marine animal species such as Atlantic salmon by feeding. Therefore, in this study we have investigated the transfer of dietary gT into salmon. To this end, fish were fed a diet supplemented with 170 ppm gT for 16 weeks whereby alpha tocopherol levels were adjusted to 190 ppm in this and the control diet. Feeding gT-rich diets resulted in a three-fold increase in gT concentrations in the liver and fillet compared to non-gT-supplemented controls. Tissue alpha tocopherol levels were not decreased indicating no antagonistic interaction between gamma- and alpha tocopherol in salmon. The concentration of total omega 3 fatty acids slightly increased in response to dietary gT. Furthermore, dietary gT significantly decreased malondialdehyde in the fillet, determined as a biomarker of lipid peroxidation. In the liver of gT fed salmon we observed an overall down-regulation of genes involved in lipid homeostasis. Additionally, gT improved the antioxidant capacity by up-regulating Gpx4a gene expression in the pyloric caeca. We suggest that Atlantic salmon may provide a marine functional source capable of enriching gT for human consumption.

Organisationseinheit(en)
Institut für Lebensmittelwissenschaft und Humanernährung
Molekulare Lebensmittelchemie und -entwicklung
Typ
Artikel
Journal
Marine drugs
Band
12
Seiten
5944-5959
Anzahl der Seiten
16
ISSN
1660-3397
Publikationsdatum
09.12.2014
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Wirkstoffforschung
Ziele für nachhaltige Entwicklung
SDG 3 – Gute Gesundheit und Wohlergehen, SDG 14 – Lebensraum Wasser
Elektronische Version(en)
https://doi.org/10.3390/md12125944 (Zugang: Offen)